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The formation of these proteins arises from many heterogeneous compounds that can be formed by the non-enzymatic reaction of free amino groups with either aldehydes or sugars (the Maillard reaction)

Grander C, Adolph TE, Wieser V, Lowe P, Wrzosek L, Gyongyosi B, et al

Despite extensive biochemical knowledge of cobalamin metabolism and its physiological importance, the optimal supplementation route for maintaining or restoring adequate vitamin B12 levels remains debated

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