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But do they actually help with weight loss
18 CeroveckiT.BojanicI.BrcicL.RadicB.VukojaI.SeiwerthS.et al (2010)

These predispositions do not predict exact B12 response, but they can flag whether you may benefit from optimized cobalamin support or whether your body may require different dosing strategies or cofactors to maximize nutrient utilization
But, if either substances are pushed too quickly the resulting damage to the tissue can cause a nasty charley horse like pain that can persist for hours or days
