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RIP and RILF affect 1750% of irradiated lung cancer patients, resulting in reduced treatment efficacy, elevated risk of mortality and disability, and compromised quality of life [35, 56]
The mTOR signaling cascade is a central regulator of autophagy, providing therapeutic targets for intervention (Zou et al
Additionally, several trials were sponsored by industry, featuring overlapping investigator teams and manufacturer involvement in study design and data analysis
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