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Khavinson Publication: Bulletin of Experimental Biology and Medicine, 2016 URL: This in vitro study examined several short peptides, including AEDG, in aging skin fibroblast cultures

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Sympathetic activation, mediated by the -ARs-Gs-adenylyl cyclase-cAMP-protein kinase A (PKA) signaling pathway, activates and phosphorylates LTCCs, increasing inward Ca 2+ current ( 2+ release from SR, which in turn increases cardiac contractility ( 2+ removal from cytosol, thus improving cardiac relaxation