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The extracellular loops of claudin molecules make hemophilic and heterophilic interactions with adjacent cells and the interactions create either barriers against or pores for the passage of selective molecules in the paracellular pathways.12,28 Numerous studies have demonstrated that claudins are the key component and backbone of TJs

This combination is particularly beneficial for skin health and rejuvenation, as it combats oxidative stress more effectively than glutathione alone

1 Deficiency is often due to a lack of B12 foods in the diet, absorption issues, and/or genetic mutations that affect uptake

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