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In line with the importance of TXNRD1 in the regulation of ferroptosis and apoptosis in AML cells, auranofin, a TXNRD1 inhibitor, impaired cell viability in AML subtypes dependent on TXRND1 for their protection against ferroptosis [53]
The PD-associated genes were obtained from DisGeNet 169,170,171 ( DisGeNET covers the full spectrum of human genetic diseases, as well as normal and abnormal traits
