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One of the possibilities is the first enzyme involved in proline metabolism, proline oxidase, as it was already speculated in the previous report (Obayashi et al
Compared to the liver, we observed that the kidney has: (1) similar increased use of energy-related metabolites and production of urea cycle and ammonia-related intermediates, suggesting a shared catabolism in AKI, and (2) higher pools of energy metabolism intermediates in AKI

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On the basis of the turnover frequency calculations, the catalytic cycle of tellurosubtilisin is faster than that of selenosubtilisin, because of the lower span energy
