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Specifically, the drug effectively inhibits the activation of the NF-B signaling pathway, leading to significant reduction in the mRNA expression levels of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1, ultimately delaying the progression of muscle atrophy [29]

Additionally, strains like Lactobacillus paracasei SH2020 and Lactobacillus kefiranofaciens ZW18 have been shown to enhance the outcomes of immunotherapies further,, suggesting their potential role in addressing chronic infections and inflammatory conditions (Fig