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Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay

The key lesson from ACE-031 was that broad TGF-beta superfamily inhibition produces unacceptable off-target effects, particularly vascular toxicity

But anyone with active cancer or high risk should talk to a healthcare professional first Limited Long-Term Human Data : Large, long-term human trials have not been completed

Fact: No human evidence demonstrates a dose-response relationship
