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[DOI] [PMC free article] [PubMed] [Google Scholar] 279.Wiegand C, Fink S, Beier O, Horn K, Pfuch A, Schimanski A, et al

Dosing protocols are all over the map across different studies

The BBB acts as both a protective shield and a regulator, ensuring the CNS is isolated from toxins, pathogens, and potentially harmful fluctuations in blood composition, such as hormones or metabolites that could disrupt normal function [3]
AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (version 5.4, released 2026-03-06) was used solely for language editing
