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Additionally, the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is a core oncogenic signaling axis frequently activated in tumors
This eliminates eight hours of cumulative exposure per night

Mller C, Wingler K, Brigelius-Floh R (2003) 3UTRs of glutathione peroxidases differentially affect selenium-dependent mRNA stability and selenocysteine incorporation efficiency
These effects were dose-dependent, emerging only at 50 mg/kg/daya level still classified as safe in animals by regulatory standards
