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Description
They can be very effective, but they also need careful monitoring

TRIUMPH-CVOT: cardiovascular outcomes trial, approximately 10,000 participants with established CVD, primary endpoint major adverse cardiovascular events (MACE), timeline 3 to 4 years

some protocols titrate further to 12.515 mg if well tolerated [2]

Quest Diagnostics lists 200-1,100 pg/ml as the normal range for vitamin B12 levels
