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Cancer immune escape: the role of antigen presentation machinery

By selectively neutralizing the most damaging reactive oxygen species, H may reduce the overall oxidative burden on the glutathione system, allowing GR to operate more efficiently within its capacity

These effects contribute to a reduction in fibrosis and the enhancement of repair processes, without compromising the healing response, as demonstrated by decreased paw swelling and improved histological outcomes in rat models [120]

Nevertheless, inactivation of GSTA4 remarkably increases cell susceptibility to chemotherapeutic agents in vitro and in the xenograft mouse model