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Description
and causes - Mayo Clinic
Lipid dysregulation promotes the pathogenesis of PD by oxidative stress and inflammation, such as proinflammatory lipid mediators of platelet-activating factors, which play a key role in the progressive neurodegeneration associated with -synuclein intracellular traffic in PD
Oxidation of guanine by reactive oxygen species, for example, can produce 8-oxo-guanine (Figures 5.52 and 5.53)
Anh FF, Pilon G, Roy D, Desjardins Y, Levy E, Marette A
