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AHK-Cu is a cosmetic topical not a drug so it is not subject to FDA drug approval

Vitamin B12 supplementation can be an important part of treatment for dogs with any of these conditions: Small intestinal bacterial overgrowth (SIBO) Surgeries that shorten bowel length Cancer of the intestinal tract Familial cobalamin deficiency (a genetic condition) Eating a vegan diet that isnt designed by a veterinary nutritionist Veterinarians will routinely run blood tests to check a dogs vitamin B12 levels after they have diagnosed any of these health problems or if the dog has symptoms that fit with a vitamin B12 deficiency

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Trazodone may not be appropriate if you: Are taking or have recently taken an MAO inhibitor (such as phenelzine or selegiline) Are taking linezolid or methylene blue Have a known allergy or hypersensitivity to trazodone Have a history of heart disease, irregular heartbeat, or QT prolongation Have a history of priapism or conditions that increase the risk of prolonged erection Have liver or kidney impairment, without close monitoring and dose adjustment Have a history of bipolar disorder or mania, without first discussing risks with your doctor Are pregnant, planning to become pregnant, or breastfeeding, without first discussing risks with your doctor This is not a complete list of precautions, contraindications, or drug interactions