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That is intentional: the two vial sizes reflect two different documented protocols and two different concentration setups, and it is a reminder never to eyeball a dose across vial sizes
The limited results indicated no measurable adverse acute effects on hepatic, renal, cardiac, or thyroid biomarkers, suggesting basic short-term tolerability
Yes, it can be slightly unpleasant and painful, but it is only a minor inconvenience
Likewise, brinzolamide may induce corneal edema [80,81]
