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This action is crucial in protecting cells from oxidative damage, which can lead to various health issues, including chronic disorders

Other factors to consider in a pharmacokinetic study may include controls to ensure compound stability in the collected samples prior to analysis, anesthesia used prior to sacrifice and/or sample collection, and sample collection tubes (serum, plasma with anticoagulant, etc.)

The long-term effects on growth hormone secretion are of specific interest, as sustained rise of IGF-1 levels (whether from endogenous or exogenous sources) can suppress growth hormone release through negative feedback at the hypothalamic and pituitary levels

Chen S, Li B, Chen L, Jiang H