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As previously stated, astrocytes exert both neuroprotective and neurodegenerative roles, depending on the molecules released by them, and the pathological or normal circumstances of their microenvironment [6]

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55,56 Genetic or pharmacological inhibition of ACSL4 inhibited ferroptosis by preventing the esterification of AA or AdA into PE, which was the only lipid oxidized in endoplasmic-reticulum-associated compartments during ferroptosis

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