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Tirzepatide, the first dual GIP/GLP-1 receptor agonist (RA), received US Food and Drug Administration (FDA) approval for the treatment of T2DM in May 2022 and for chronic weight management in November 2023 [4]

The primary environmental cause of hypermethioninemia is deficiency in vitamin B6

Further investigations are also required to isolate the bioactive compounds responsible for immunity-boosting, drug development, antioxidant, anti-inflammatory, antibiotic, and antimicrobial activities in their pure form
This suggests that metabolic rewiring via lipid pathways is a non-canonical mechanism by which the autophagy-ferroptosis balance is tilted toward tumor promotion