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In this metabolic pathway, G6PD supplies reducing energy to red blood cells (RBCs) through NADPH and glutathione (GSSG), which can protect RBCs from oxidative stress

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It suppresses Th17 cell responses, inhibits dendritic cell maturation, downregulates NADPH oxidase, and enhances glutathione antioxidant pathways to reduce reactive oxygen species and mitochondrial damage (10)
