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Fungal cell wall component -glucan induces IL-1 release by binding to C-type lectin domain containing 7 A (CLEC7A) on Kupffer cells, promoting hepatitis, steatosis, and hepatocyte death, thereby aggravating ALD 16

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First, glutamate-cysteine ligase (GCL) catalyzes the conjugation of cysteine and glutamate, which results in the formation of \(\gamma\)-glutamylcysteine

125,128 However, most fragility fractures (which are definitively diagnostic for osteoporosis) occur in individuals with BMD scores that do not indicate osteoporosis