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doi: 10.1007/s11064-012-0935-6

3 Ferroptosis and inflammation When numerous exogenous and endogenous factors damage cells, tissues, and organs, a series of complex local and systemic reactions, referred to as the inflammatory response, occur to limit and eliminate the damage factors, remove and absorb necrotic tissues and cells, and repair the damage (136, 137)

In patients with IBD, intestinal macrophages exhibit dual metabolic characteristics: during the acute phase, macrophages tend to undergo M1 polarization, accompanied by elevated NO levels

ALA also supports the recycling of other antioxidants in the body, contributing to improved antioxidant efficiency