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It is supplied as a lyophilized powder for in-vitro and pre-clinical study, not for human use

In a 12-week clinical trial by Leyden et al

ROS production increased dramatically, but that the yield of transgenic plants was much lower than that of the wild type, indicating that in vivo GB accumulation can reduce ROS production by case of heat stress

Though this specificity for granule cell pathology is unclear, differential expression of GABA A receptor subunits (6 GABA A receptor subunits on granule cells and 1 on the Purkinje cells) and NMDA subunits have been postulated (higher NMDAR2 expression in granule cells and NMDAR1 in Purkinje cells) as the likely causes