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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Lamba G, Ambrale S, Lee B, et al

Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]

Timing : The patient may provide the sample anytime

The studys limitations include the cross-sectional nature, which precludes establishing causality, self-reporting of anthropometric and demographic data, which might lead to bias, and unidentified confounding
