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For instance, AAV-based vectors have a limited capacity of 4.7-kb, which prohibits the integration of multiple genes [85]
For further differentiation into HBs, a combined protocol of BMP4, IWR-1, and TGF inhibitor SB431542 eliciting hepatic markers, including fetoprotein (AFP), albumin (ALB), and prospero homeobox 1 (PROX1) was established (Touboul et al., 2016)
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10.1016/S0140-6736(21)00233-6 [DOI] [PubMed] [Google Scholar] 390.Jiang, K
