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127 In skeletal muscle, TFEB supports mitochondrial homeostasis by activating mitophagy-related genes such as PINK1, PRKN , and BNIP3 , which are essential under metabolic or exercise-induced stress

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Our search on clinicaltrials.gov (ClinicalTrials.gov) identified 25 trials using GSH and associated compounds (specifically tGSH, GSH/GSSG, GPx and GR) as a treatment (3/25), an outcome measure (17/25), or both (5/25) (Supplementary Fig

Lancet 381 , 117124 (2013)