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Description
The compound is best known as an inhibitor of nicotinamide Nmethyltransferase (NNMT), an enzyme implicated in adipose tissue energy handling and nicotinamide adenine dinucleotide (NAD+) turnover.

Dose-response relationships appear to be tissue-specific, with adipose tissue showing high sensitivity while other tissues may require higher concentrations for detectable effects

Master's athletes, as growth hormone production can slow a bit with age
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