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It is widely found in plants, animals, fungi, and microorganisms

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doi:10.1007/s00405-014-3175-3 Talaat HS, Kabel AM, Khaliel LH, Abuhadied G, El-Naga HA, Talaat AS

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Arch Oral Biol

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This suggests that the IGF axis may play a more significant role in later stages of adenoma growth and transformation, or that only certain adenomas are responsive to IGF

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