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The cultures were incubated at 30 C with agitation at 250 rpm for additional 48 h

although this patient developed hepatotoxicity and was treated with NAC and dialysis, it was suggested that this case was less clinically severe than would be expected in an adult [51]

By utilising non-traditional antimicrobial mechanisms like ROS generation and pH/enzyme-triggered release, these multifunctional platforms not only modulate dysbiosis and disrupt resilient biofilms, but they also achieve up to 90% wound closure in preclinical models

Ribose-5-phosphate isomerase (RPI) and ribulose-5-phosphate epimerase (RPE) catalyze reversible reactions that convert Ru5P to R5P and xylulose-5-phosphate (Xu5P), respectively