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No Clinical Oversight Not manufactured under FDA-regulated quality or clinical standards
[DOI] [PubMed] [Google Scholar] 889
Nuclear Nrf2 levels have been identified to be substantially reduced in the brains of Alzheimers patients [99]
Currently, neurotoxins that target complex I like 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and rotenone are used to induce parkinsonism in both in vitro and in vivo models for research, and treatment with these drugs is known to induce oxidative stress [11,12]
