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This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol
The increase in proinflammatory cytokines is hypothesized to deplete GSH to facilitate replication of SARS-CoV-2 and other viruses, leading to exacerbated symptoms [36]
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GSH levels in the LH region were depleted significantly, but LH susceptibility did not alter in the PD cohort compared to HC
