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PTSD from early trauma can worsen MSIDS and make it more resistant, so counseling can help

doi: 10.1016/j.ijmm.2011.04.007 42 FoxE

However, so far, there have been few reports on the use of such drugs with BBB-crossing capability for the treatment of PD

Duan Y, Li F, Li Y, Tang Y, Kong X, Feng Z, Anthony TG, Watford M, Hou Y, Wu G, Yin Y