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AOD-9604 Research Protocols & Administration Dosing in Published Research Research investigations have employed diverse AOD-9604 doses across species and administration routes: Rodent studies: 250-500 mcg/kg orally or intraperitoneally was most common for obesity research Rabbit models: 0.25 mg per joint for osteoarthritis studies (intra-articular injection) Pig pharmacokinetic studies: 1.5 mg/kg IV and 2 mg/kg oral for metabolism characterization Human clinical trials: Oral doses of 0.25-10 mg daily

Other B vitamins in their coenzyme form may be helpful

Its mechanism is direct lipolysis, making it a different tool with different patient profiles

It is available only through research chemical suppliers and some compounding pharmacies, usually labeled not for human use Australia: Classified as a Schedule 4 prescription-only medicine, meaning it can only be legally obtained with a doctors prescription