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Early studies recognized that mammals: (i) lack the capacity to catabolize l-carnitine

Because your intestines can only absorb so much at once, and your kidneys continuously waste it, a single large daily dose would simply be excreted, leaving your heart and muscles unprotected for the rest of the day [11] [7]

doi:10.1016/j.bjps.2009.05.039 Pisano C, Pratesi G, Laccabue D, Zunino F, Lo Giudice P, Bellucci A, Pacifici L, Camerini B, Vesci L, Castorina M, Cicuzza S, Tredici G, Marmiroli P, Nicolini G, Galbiati S, Calvani M, Carminati P, Cavaletti G (2003) Paclitaxel and cisplatin-induced neurotoxicity: a protective role of acetyl-l-carnitine

Earlier research discovered that increased Lp(a) levels are linked to the risk of Alzheimer's disease and vascular dementia, and shifts in Lp(a) may help detect vascular damage in Alzheimer's disease or vascular dementia [149]
