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Jasmonic acid plays a key role in defense responses against both biotic and abiotic stresses, while also regulating processes such as seed dormancy, fruit ripening, and senescence
In this report, we test this hypothesis by treating the HRAS G12V -transformed ovarian epithelial cells, mutant KRAS -harboring pancreatic and colon cancer cells of mouse and human origins, as well as cancer xenografts, with diphenyleneiodonium (DPI) and buthionine sulfoximine (BSO) combination, which inhibit NOX activity and glutathione biosynthesis, respectively
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