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In simple terms, the molecules become less likely to stick together, which can help the peptide move into a clearer and more uniform solution

doi: 10.1038/s41392-023-01452-1 113 FreyALundingLPWegmannM
No improvement was seen on this regimen

This priming stage is essential for the viral capsid to be released into host cells, as it exposes hydrophobic FP on the S2 subunit, which is then inserted into the host cell membrane