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Feb 2015;9(2):501-506

Evidence supports that IL-6 has an ability to suppress the enzymes iodothyronine deiodinases type I (D1) and II (D2), reducing the conversion of prohormone thyroxine T4 to its active form T3, which ensures the deregulation of glutamate cysteine ligase (GCL) and the successive reduction of GSH synthesis [72,73]

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have shown that patients with septic shock who are admitted to the ICU ( N = 18) have a significantly higher median expression of syndecan-1 than healthy individuals (111)