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Factors include: Use of different salt forms Particle size of the drug (micronization can improve dissolution), and Type and amount of inactive ingredients, or excipients , used in the formulation

Given the heightened presence of volatile sulfur compounds in ripe durian pulp 28 , known for their contributions to the unpleasant roasty and onion-like odor 36 , our primary objective in this investigation was to explore the protective effects of UDE containing no volatile sulfur compounds against oxidative stress-induced neurotoxicity and neuroinflammation in human cells

Within hepatocytes further accumulation leads to deposition in lysosomes (Rhodamine positive staining)

10.1016/j.freeradbiomed.2025.09.049 103 LyuC.XiaoH.YinX.LiZ.HanC.XuR