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Cells sense extracellular oxidative stimuli to decrease G6PD acetylation in a SIRT2-dependent manner
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Preclinical studies of stem-cell based treatments for Parkinsons and disease modeling efforts iPSCs and 3D brain organoids have significantly advanced our understanding of PD pathophysiology and assisted in drug development by allowing us to replicate the specific mutations commonly found in familial PD (fPD), including those in -synuclein [74, 75]

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V., Semenchenko, A
