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The schistosomicidal activities of PZQ and of potassium antimonial tartrate, a drug used in the past for schistosomiasis and a TGR inhibitor, are reduced in immunosuppressed mice 65 , indicating a crucial role of the host immune system in the mechanism of action of schistosomicidal agents in vivo
These findings confirm that the vCLAMP core protein Mcp1 plays an essential role in the hyphal development and virulence of C
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A dose finding phase II trial of isatuximab (SAR650984, Anti-CD38 mAb) as a single agent in relapsed/refractory multiple myeloma
