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The BTD gene is located on chromosome 3p25.1 and is composed of 10 exons that generate 41 alternatively spliced mRNAs that collectively encode nine distinct protein isoforms

20 Studies have also revealed that MGST2 catalyzes the activation of GSH, resulting in the formation of a thiolate essential for both GSH peroxidase activity and GSH conjugation reactions with electrophilic substrates such as 1-chloro-2,4-dinitrobenzene