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It is one of the most commonly used intravenous solutions in healthcare settings due to its compatibility with the human body

Twenty four published articles were eligible for inclusion in this systematic review in which a range of treatment regimens were evaluated including both B12 monotherapy and B12 in combination with other vitamins or conventional treatments, such as gabapentinoids

Cutaneous active vasodilation in humans is mediated by cholinergic nerve cotransmission

[62] [63] The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting non-toxic cyanocobalamin is excreted in urine