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Another important mechanism [22] involves its ability to inhibit nuclear factor kappa B (NF-B), a transcription factor responsible for the transcription and production of multiple pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-), IL-1, and IL-6
Cytokines such as interleukin-1 family members are released to generate inflammatory reactions and require gasdermin since these cytokines cannot alone result in pore formation (212, 515)
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A., Dunn-Lewis, C.,
