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With further in-depth analysis of its regulatory network and continued optimization of activator design, SIRT1 holds significant potential as a breakthrough target for multi-pathway, systemic, and precise intervention in MASLD

It is sometimes part of organ preservation fluids, e.g., for heart transplantation (Chen et al., 2019)

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compared the mRNA and protein levels of neuroplasticity factors, synaptic proteins, angiogenic factors, and regulatory molecules (e.g., BDNF, TrkB, CREB, and HIF-1) in mice following either exercise or RIPostC therapy