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In response, current clinical guidelines strictly contraindicate -carotene supplementation in active smokers and individuals with a history of asbestos exposure (246)
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In a few cases, a cysteine S -conjugate sulfoxide has been shown to be a substrate of purified cysteine S -conjugate -lyases yielding pyruvate and ammonium ion (Larsen and Stevens, 1986, Tomisawa et al., 1986)