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Recent advances in Alzheimers disease: Mechanisms, clinical trials and new drug development strategies

One of the major changes that occur during aging is the dysregulation of the immune response that leads to a chronic low-grade inflammatory state, which is thought to be a major risk factor for multiple chronic age-related dysfunctions and/or diseases, including hair loss, neurodegeneration, cancer, osteoporosis, cardiovascular disease, atherosclerosis, sarcopenia, and T2DM (Fig

250 Additionally, genetic information can inform nutritional and supplementation strategies to support tissue health and recovery

They also reported that human platelets are glycine responsive and express glycine gated chloride channels [70]