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Notably, small molecule inhibitors have been identified that induce a conformational shift that precludes PrfA binding to DNA (Good et al., 2016
Depending on the severity of the deficiency, this can involve oral B12 supplements, B12 injections, or high-dose B12 supplements prescribed by a healthcare professional
Sleep Circadian Rhythm
You can get vitamin B12 naturally by maintaining a healthy diet and lifestyle
