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Description
To elucidate the molecular mechanisms underlying MG-induced ferroptosis and kidney injury, we performed an intersection analysis of these differentially expressed genes with known ferroptosis-related gene sets, thereby identifying targeted genes that may be associated with ferroptosis-related mechanisms
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Control cells were treated with H 2 O 2 (1 mM) for 30 min as a positive control for increased ROS production
Furthermore, ferroptosis-associated genes RBMS1, NOX4, FABP4, CYB5R1, CPEB1, and ATM, exhibit significant associations with immune cell infiltration and adverse clinical outcomes [172]
