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These findings suggest that under iron overload, astrocyte-mediated ferritin secretion may mitigate oxidative stress and ferroptosis in dopaminergic neurons, a key process implicated in PD pathogenesis (Zhang et al., 2022b)

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doi: 10.1007/s13197-018-3035-z, 192 XieY.PanM.GaoY.ZhangL.GeW.TangP

The Wnt agonists and antagonists from the DP predominantly act on matrix cells despite their autocrine potential To explore the proposition that Wnt signaling activity in the bulb is normally reduced during late anagen, the Axin2-lacZ Wnt-reporter allele 35 was introduced in both control and dMF1/2 mutant mice