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Description
Clinical evidence on the involvement of gut-related factors in osteoporosis led us to undertake the core concept of the gutbone axis and systematically summarize that the intestinal intrinsic structure, gut microbiota, and derived metabolites, with the immune and endocrine routes as the intermediate transitions, attain a bidirectional interplay with skeletal tissue through the gutbone axis
To advance the translation of basic research into novel therapeutic applications
doi: 10.1093/humupd/dmaa029
Vanselow, J
